Intracellular structures and the fatty acid oxidase system of rat liver.

In an earlier investigation it was shown that enzymatic oxidation of octanoate occurred in saline suspensions of washed particulate matter separated from saline homogenates of rat liver by centrifugation, when these were supplemented with adenosine triphosphate and Mg++.l These preparations also catalyze the reactions of the Krebs tricarboxylic acid cycle. Further study of the properties of the enzyme complex has revealed that the oxidation of octanoate requires the presence of cytochrome c,